Charles Natanson Selected Research

Shock

1/2021	Mechanistic insights into cell-free hemoglobin-induced injury during septic shock.
1/2018	Haptoglobin improves shock, lung injury, and survival in canine pneumonia.
10/2017	Parenteral irons versus transfused red blood cells for treatment of anemia during canine experimental bacterial pneumonia.
3/2014	Mortality in patients with hypovolemic shock treated with colloids or crystalloids.
2/2014	Washing older blood units before transfusion reduces plasma iron and improves outcomes in experimental canine pneumonia.
12/2012	Beneficial effects of stress-dose corticosteroid therapy in canines depend on the severity of staphylococcal pneumonia.
1/2012	Efficacy of selective mineralocorticoid and glucocorticoid agonists in canine septic shock.
12/2010	Anthrax lethal and edema toxins produce different patterns of cardiovascular and renal dysfunction and synergistically decrease survival in canines.
1/2009	Growing insights into the potential benefits and risks of activated protein C administration in sepsis: a review of preclinical and clinical studies.
11/2006	Preclinical trial of L-arginine monotherapy alone or with N-acetylcysteine in septic shock.

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Charles Natanson Research Topics

Disease

38	Sepsis (Septicemia) 01/2021 - 05/2002
18	Septic Shock (Toxic Shock Syndrome) 01/2021 - 05/2002
14	Infections 01/2021 - 07/2003
11	Shock 01/2021 - 07/2004
8	Lung Injury 01/2021 - 11/2003
7	Hemolysis 01/2019 - 12/2005
6	Pneumonia (Pneumonitis) 01/2021 - 11/2003
6	Staphylococcal Pneumonia 12/2019 - 07/2003
5	Critical Illness (Critically Ill) 12/2014 - 12/2004
4	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 12/2019 - 06/2007
3	Pulmonary Hypertension 01/2021 - 02/2013
3	Body Weight (Weight, Body) 01/2018 - 03/2003
2	Bacterial Pneumonia 10/2017 - 11/2003
2	Hemorrhagic Shock 11/2015 - 05/2008
2	Inflammation (Inflammations) 04/2011 - 03/2006
2	Hemorrhage 01/2009 - 01/2009
2	Myocardial Infarction 09/2008 - 05/2008
2	Peritonitis 11/2006 - 03/2003
1	Acidosis 01/2021
1	Hypoxia (Hypoxemia) 10/2019
1	Methemoglobinemia 10/2019
1	Anemia 10/2017
1	Reperfusion Injury 11/2015
1	Acute Lung Injury 10/2014
1	Necrosis 10/2013
1	Bacteremia 12/2012
1	Hypotension (Low Blood Pressure) 01/2012
1	Edema (Dropsy) 12/2010
1	Adrenal Insufficiency (Adrenal Gland Hypofunction) 02/2010
1	Acute Kidney Injury (Acute Renal Failure) 01/2008
1	Hypoglycemia (Reactive Hypoglycemia) 01/2008
1	Escherichia coli Infections 03/2006

Drug/Important Bio-Agent (IBA)

11	Hemoglobins (Hemoglobin)IBA 01/2021 - 12/2005
8	IronIBA 01/2021 - 02/2014
7	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2018 - 11/2002
7	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2014 - 06/2004
7	Protein CIBA 01/2009 - 01/2003
6	Lactic Acid (Lactate)FDA LinkGeneric 01/2021 - 01/2012
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021 - 11/2006
5	Anti-Bacterial Agents (Antibiotics)IBA 02/2020 - 02/2010
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2013 - 03/2003
4	Oxygen (Dioxygen)IBA 01/2021 - 05/2008
4	Hydrocortisone (Cortisol)FDA LinkGeneric 12/2014 - 07/2004
3	Transferrin (beta 2 Transferrin)IBA 11/2015 - 02/2014
3	GlucocorticoidsIBA 01/2012 - 07/2004
3	E5564IBA 04/2011 - 03/2006
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2020 - 09/2004
2	HaptoglobinsIBA 12/2019 - 01/2018
2	NitratesIBA 10/2019 - 12/2005
2	NitritesIBA 10/2019 - 08/2008
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 11/2015 - 12/2004
2	Dexamethasone (Maxidex)FDA LinkGeneric 12/2014 - 01/2012
2	Adrenocorticotropic Hormone (ACTH)FDA Link 12/2014 - 02/2010
2	AldosteroneIBA 12/2014 - 01/2012
2	Colloids (Colloid)IBA 03/2014 - 01/2008
2	hemoglobin ASIBA 12/2012 - 08/2008
2	eritoranIBA 04/2011 - 01/2010
2	CreatinineIBA 01/2009 - 03/2003
2	CoagulantsIBA 01/2009 - 06/2004
2	Blood Substitutes (Artificial Blood)IBA 09/2008 - 05/2008
2	EndotoxinsIBA 03/2006 - 03/2003
2	AnticoagulantsIBA 04/2005 - 06/2004
1	Blood Proteins (Serum Proteins)IBA 12/2019
1	ChromiumIBA 01/2019
1	Ferrosoferric Oxide (Magnetite)FDA Link 10/2017
1	Saccharated Ferric Oxide (Venofer)FDA Link 10/2017
1	C-Reactive ProteinIBA 11/2015
1	Dihydrotachysterol (AT 10)IBA 12/2014
1	boldenone undecylenate (Equipoise)IBA 10/2014
1	AntibodiesIBA 10/2013
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2012
1	Oxacillin (Prostaphlin)FDA LinkGeneric 12/2012
1	Interleukin-6 (Interleukin 6)IBA 12/2012
1	Tigecycline (Tygacil)FDA Link 06/2012
1	Desoxycorticosterone (Deoxycorticosterone)IBA 01/2012
1	MineralocorticoidsIBA 01/2012
1	CytoFabIBA 11/2011
1	Immunoglobulin FragmentsIBA 11/2011
1	AZD9773IBA 11/2011
1	LipopolysaccharidesIBA 04/2011
1	Toll-Like Receptor 4IBA 04/2011
1	Heparin (Liquaemin)FDA LinkGeneric 04/2009
1	drotrecogin alfa activated (Xigris)FDA Link 01/2009
1	Nitrite Reductases (Nitrite Reductase)IBA 08/2008
1	Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric 08/2008
1	Glucose (Dextrose)FDA LinkGeneric 01/2008
1	Hydroxyethyl Starch Derivatives (Pentastarch)FDA Link 01/2008
1	Starch (Cornstarch)IBA 01/2008
1	Ringer's LactateIBA 01/2008
1	Insulin (Novolin)FDA Link 01/2008
1	Acetylcysteine (Siran)FDA LinkGeneric 11/2006
1	Arginine (L-Arginine)FDA Link 11/2006
1	Lipid AIBA 03/2006

Therapy/Procedure

19	Therapeutics 12/2019 - 11/2002
2	Resuscitation 11/2015 - 01/2008
2	Early Goal-Directed Therapy 02/2010 - 05/2002
2	Critical Care (Surgical Intensive Care) 02/2010 - 06/2007
1	Artificial Respiration (Mechanical Ventilation) 12/2010
1	Counterpulsation (External Counterpulsation) 01/2009
1	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2008